See Shionogi-Sponsored Publications

Publications

Here, you can review available Shionogi-sponsored publications. If you would like an electronic copy of one of the journal publications on this page, please contact
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Information about investigational compounds or investigational uses of products does not imply FDA approval of these compounds or uses, nor does it establish the safety or efficacy of these compounds or uses. There is no guarantee that the investigational compounds or investigational uses of products will receive FDA approval. Shionogi does not recommend or suggest use of its products in a manner inconsistent with FDA-approved labeling.

 
Zatolmilast
Phase 2
Fragile X syndrome

Inhibition of phosphodiesterase-4D in adults with fragile X syndrome: a randomized, placebo-controlled, phase 2 clinical trial

Published:
2021
Authors:
Berry-Kravis EM, Harnett MD, Reines SA, et al.
 
Zatolmilast
Review
Fragile X syndrome

Design and synthesis of selective phosphodiesterase 4D (PDE4D) allosteric inhibitors for the treatment of fragile X syndrome and other brain disorders

Published:
2019
Authors:
Gurney ME, Nugent RA, Mo X, et al.
 
Zatolmilast
Review
Fragile X syndrome

Genetic association of phosphodiesterases with human cognitive performance

Published:
2019
Authors:
Gurney ME
 
Zatolmilast
Preclinical
Fragile X syndrome

Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice

Published:
2018
Authors:
Zhang C, Xu Y, Chowdhary A, et al.
 
Zatolmilast
Preclinical
Fragile X syndrome

Multiple behavior phenotypes of the fragile-X syndrome mouse model respond to chronic inhibition of phosphodiesterase-4D (PDE4D)

Published:
2017
Authors:
Gurney ME, Cogram P, Deacon RM, et al.